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Cytomegalovirus Immune Globulin (Human), Intravenous

 What are other names for this medicine?
 What is this medicine used for?
 What should my healthcare provider know before I take this medicine?
 How do I use it?
 What should I watch out for?
 What are the possible side effects?
 What products might interact with this medicine?

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Pronunciation: sy-toh-MEG-a-loh-vy-rus i-MYOON GLOB-yoo-lin




What are other names for this medicine?

Type of medicine: immune globulin

Generic and brand names: cytomegalovirus immune globulin (human), intravenous; CytoGam

What is this medicine used for?

This medicine is given by IV infusion (slow drip through a needle into a large vein) to prevent a viral infection called cytomegalovirus disease. This disease often follows heart, kidney, liver, lung, or pancreas transplants.

This medicine may be used to treat other conditions as determined by your healthcare provider.

What should my healthcare provider know before I take this medicine?

Before taking this medicine, tell your healthcare provider if you have ever had:

Also tell your provider if you have received any vaccines in the past few months.

Females of childbearing age: Talk with your healthcare provider if you are pregnant or plan to become pregnant. It is not known whether this medicine will harm an unborn baby. Do not breast-feed while taking this medicine without your healthcare provider's approval.

How do I use it?

The infusions will be given by your healthcare provider. The infusions are given over a period of time depending on your response and the side effects you may have.

What should I watch out for?

You may need to have blood tests regularly to see how this medicine affects you. Keep all appointments for these tests.

This medicine is made from human tissue. It is tested for viruses such as hepatitis and HIV. The risk of getting an infection from this medicine is very low, but it is still possible. Talk with your healthcare provider about this.

This medicine may cause serious kidney problems. Signs of kidney problems include urinating less often, unexplained bloating or swelling, and shortness of breath. If you have these symptoms while being treated with this medicine, contact your healthcare provider right away.

This medicine may cause an infusion reaction. Tell your healthcare provider right away if you have:

If you develop hives, an itchy rash, or peeling skin, stop taking the medicine and contact your provider right away.

Adults over the age of 65 may be at greater risk for side effects.

If you need emergency care, lab tests, surgery, or dental work, tell the healthcare provider or dentist you have received this medicine.

What are the possible side effects?

Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your healthcare provider if you have any side effects that continue or get worse.

Life-threatening (Report these to your healthcare provider right away. If you cannot reach your healthcare provider right away, get emergency medical care or call 911 for help): Allergic reaction (hives; itching; rash; trouble breathing; tightness in your chest; swelling of your lips, tongue, and throat); sudden weakness, numbness, or tingling, especially on one side of your body; sudden or severe headache; sudden trouble with vision, speech, balance, or walking.

Serious (report these to your healthcare provider right away): Chest pain, fast or irregular heartbeat, severe or sudden headache, dizziness, stiff neck, fever, chills, sensitivity to light, seizures, unusual drowsiness, unexplained nausea or vomiting, decreased urination, sudden weight gain or bloating, trouble breathing, coughing up blood, redness or pain in calf; dark or bloody urine, loss of feeling or movement in any part of your body; unusual bleeding or bruising, extreme weakness, muscle or joint pain, light-colored bowel movements, yellowing of the skin or eyes, swelling in the legs or arms, or any unexplained swelling, severe skin redness or blisters, peeling skin, pain or burning at the injection site.

Other: Flushing, back pain, fever, mild nausea or vomiting, mild wheezing.

What products might interact with this medicine?

This medicine may interfere with live virus vaccines if given within 3 months of each other. Do not have any vaccines without getting your healthcare provider's approval first.

If you are not sure if your medicines might interact, ask your pharmacist or healthcare provider. Keep a list of all your medicines with you. List all the prescription medicines, nonprescription medicines, supplements, natural remedies, and vitamins that you take. Be sure that you tell all healthcare providers who treat you about all the products you are taking.


This advisory includes selected information only and may not include all side effects of this medicine or interactions with other medicines. Ask your healthcare provider or pharmacist for more information or if you have any questions.

Keep all medicines out of the reach of children.

Do not share medicines with other people.

healthinformatics info

Reference Sources:

Cytogam (cytomegalovirus immune globulin intravenous). 2012 CSL Behring. Accessed Sept. 20 2015 from http://labeling.cslbehring.com/PI/US/Cytogam/EN/Cytogam-Prescribing-Information.pdf.

Cytomegalovirus immune globulin. 2015 Clinical pharmacology Online. Accessed Sept. 20, 2015 from http://www.clinicalpharmacology.com.

Lexi-Interact. 2015 LexiComp. Accessed Sept. 20, 2015 from http://www.lexi.com.

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Last Modified: 2015-09-25

Last Reviewed: 2015-09-25

Website Updated: April 2016

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This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.

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