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Newborn Anemia

 What is newborn anemia?
 What is the cause?
 What are the symptoms?
 How is it diagnosed?
 How is it treated?
 How can I take care of my child?

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What is newborn anemia?

A baby who has anemia has fewer healthy red blood cells than normal. The red blood cells carry oxygen in the blood and deliver it to the rest of the body.

What is the cause?

Throughout our lives red blood cells get old and break down and our bodies make new red blood cells to replace them. Newborn babies don't start to make new red blood cells until they are about 1 month old. As some of the older red blood cells start to break down, your baby may not have enough new red cells to replace them for the first 2 or 3 months of life. For every newborn baby, this causes a mild type of anemia called physiologic or normal anemia. Once a baby starts making new red blood cells, the red blood cell count gradually goes back to normal.

Some newborns may become more anemic than normal because of:

  • Blood loss. Sometimes a baby loses blood during birth.
  • Rapid breakdown of red blood cells. Red blood cells may break down faster than normal. This can happen, for example, if the mother and baby do not have the same blood type.
  • Slow red blood cell production. Some babies may take longer to start making red blood cells. This can be caused by a lack of iron or other nutrients in the baby’s blood, an infection, or a problem with the blood-forming cells.
  • Premature birth. Premature babies have fewer red blood cells at birth and their red blood cells break down faster. They may also lose blood from frequent blood tests.

What are the symptoms?

Most babies don’t have any symptoms from normal newborn anemia. When a baby does have symptoms of anemia, they happen because the cells in the body are not getting enough oxygen from the blood. Symptoms may include:

  • Being sleepier or more tired than normal
  • Pale or yellowish skin
  • Fast heartbeat
  • Fast breathing rate

How is it diagnosed?

A baby’s red blood cells can be counted with a simple blood test.

How is it treated?

Anemia is normal for newborns and does not need to be treated unless it causes a problem for the baby or the blood count drops too low.

Iron is needed to make red blood cells. Your healthcare provider may recommend that you give your baby iron drops or iron-fortified formula.

Babies who have symptoms, and premature babies, may need a transfusion of blood, which means the baby may be given red blood cells from someone else. The smaller a premature baby is, the more likely it is that the baby will need 1 or more transfusions in the first 2 months of life. Usually the blood is from volunteers who donate to a blood bank. It may also be possible for family members to donate blood for the baby.

How can I take care of my child?

Don’t give your baby iron unless it’s prescribed by your provider and don’t give more than prescribed. Ask your provider how long your baby may need an iron supplement.

Follow your child’s healthcare provider's instructions. Ask your provider:

  • How and when you will hear your child’s test results
  • How long it will take for your child to recover
  • How to take care of your child at home
  • What symptoms or problems you should watch for and what to do if your child has them

Make sure you know when your child should come back for a checkup. Keep all appointments for provider visits or tests.

healthinformatics info


von Lindern JS,Lopriore E. Management and prevention of neonatal anemia: current evidence and guidelines. Expert Review of Hematology; 2014, Vol. 7, No. 2 , Pages 195-202

Anemia in the Newborn, Merck Manual Online Medical Library. Accessed from http://www.merck.com/mmhe/sec23/ch264/ch264q.html.

Kates, Erica Hyman, and Kates, Jacqueline S. Anemia and Polycythemia in the Newborn, Pediatrics in Review 2007 28: 33-34.

Nelson Textbook of Pediatrics, 19th ed. Robert M. Kliegman, MD, Bonita M.D. Stanton, MD, Joseph St. Geme, Nina Schor, MD, PhD and Richard E. Behrman, MD. Elsevier. 2011.

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Last Modified: 2015-03-16

Last Reviewed: 2015-03-16

Website Updated: August 2015

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Published by RelayHealth. © 2014 RelayHealth and/or one of its affiliates. All Rights Reserved.

This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.

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