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Formula or Breast Milk: How to Make High-Calorie

(En español, presione aquí)

 Breast-Fed Babies (Full-Term and Premature)
 Formula-Fed Full-Term Babies
 Formula-Fed Premature Babies

Normal breast milk or formula usually has 20 calories per ounce. Most babies do well on regular breast milk or formula. Your baby may need high calorie breast milk or formula if she is smaller than normal or gains less weight than expected.

Do not give your baby high calorie milk or formula unless your healthcare provider tells you to do so. It may cause health problems if your baby can’t digest it properly.

High calorie milk may be 22 or 24 calories per ounce. It depends on how many calories your baby needs. You can make high calorie milk using formula or pumped breast milk.

Some formulas are made just for premature infants. These are called premature follow-up formulas. They have extra calories when you follow package directions. These formulas should not be used by babies who were full-term. You do not need to use a special premature formula to fix high-calorie breast milk for a premature baby. Regular formula works fine.

Measure carefully when making high-calorie formula. Use a special measuring spoon to make sure you get the right dose. The average household teaspoon may not hold the right amount.

Breast-Fed Babies (Full-Term and Premature)

Formula-Fed Full-Term Babies

Formula-Fed Premature Babies

Your provider may suggest that you use a special premature follow-up formula. You can buy these products at the store.

To make 22-calorie per ounce formula:

Mix 2 scoops of premature follow-up formula with 4 ounces (118 mL) of water.

Do not add sugar, honey, or any other sweetener to the milk or formula. Never give honey to babies. Honey may cause a serious disease called botulism in children less than 1 year old.

Discard bottles of formula left out of the refrigerator for 1 hour or more. Throw away any refrigerated formula after 24 hours.

Call your healthcare provider if:

healthinformatics info


Brizee, MS, RD, CD, Lori S. "Increasing Caloric Concentration of Infant Formula." University of Washington. Children's Hospital and Regional Medical Center, Seattle, Washington. Web. 23 Nov. 2010. .

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Last Modified: 2013-02-13

Last Reviewed: 2012-11-12

Website Updated: October 2014

Written by Robert Brayden, MD, Professor of Pediatrics, University of Colorado.
Published by RelayHealth. © 2014 RelayHealth and/or one of its affiliates. All Rights Reserved.

This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.

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